Figure 5.

(A) Goodness of fit of a Gaussian model using activation of the CDH1 gene as an example. Gaussian distributions are represented as box and whisker plots for activating (B) and inactivating (C) genes. Yellow boxes and blue whiskers represent the 50% and 95% confidence intervals of the normal curve respectively, with the means shown as black lines. Cumulative distributions derived from the Gaussian model are overlaid for genes that are activated (D) or inactivated (E) during the course of reprogramming.