Table 1. 14-3-3σ protein expression during cancer progression by IHC analysis.

Cancer progression	Immunostaining		P
	Low	High
NEE	9(25.5%)	31(77.5%)	: P = 0.087: P = 0.000
Low grade intraepithelial neoplasia	16(43.2%)	21(56.8%)	: P = 0.000: P = 0.090
High grade intraepithelial neoplasia	21(65.6%)	11(34.4%)	: P = 0.001: P = 0.389
ESCC	124(73.8%)	44(26.2%)

Note: Low grade intraepithelial neoplasia comprises mild & moderate dysplasia; High grade intraepithelial neoplasia comprises severe dysplasia & carcinoma in situ.