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. 2014 Apr 17;9(4):e95386. doi: 10.1371/journal.pone.0095386

Table 2. Association between 14-3-3σ expression and clinicopathological parameters of ESCC.

Variable IHC expression
Low expression (n = 124) High expression (n = 44) P
Age <60 38(22.6%) 17(10.1%) 0.354
≥60 86(51.2%) 27(16.1%)
Gender Male 94(56.0%) 31(18.5%) 0.547
Female 30(17.9%) 13(7.7%)
Histological grade* Well differentiation 12(7.1%) 16(9.5%) 0.000
Moderate differentiation 73(43.5%) 18(10.7%)
Poor differentiation 39(23.2%) 10(6.0%)
T stage T1+T2 22(13.8%) 10(6.3%) 0.368
T3+T4 98(61.3%) 30(18.8%)
Lymph node metastasis No 71(43.3%) 26(15.9%) 0.719
Yes 51(31.1%) 16(9.8%)
TNM stage I–II 73(46.8%) 24(15.4%) 1.0
III–IV 45(28.9%) 14(9.0%)

*Well-differentiation vs. Moderate differentiation+Poor differentiation.