Table 2. Association between 14-3-3σ expression and clinicopathological parameters of ESCC.
Variable | IHC expression | |||
Low expression (n = 124) | High expression (n = 44) | P | ||
Age | <60 | 38(22.6%) | 17(10.1%) | 0.354 |
≥60 | 86(51.2%) | 27(16.1%) | ||
Gender | Male | 94(56.0%) | 31(18.5%) | 0.547 |
Female | 30(17.9%) | 13(7.7%) | ||
Histological grade* | Well differentiation | 12(7.1%) | 16(9.5%) | 0.000 |
Moderate differentiation | 73(43.5%) | 18(10.7%) | ||
Poor differentiation | 39(23.2%) | 10(6.0%) | ||
T stage | T1+T2 | 22(13.8%) | 10(6.3%) | 0.368 |
T3+T4 | 98(61.3%) | 30(18.8%) | ||
Lymph node metastasis | No | 71(43.3%) | 26(15.9%) | 0.719 |
Yes | 51(31.1%) | 16(9.8%) | ||
TNM stage | I–II | 73(46.8%) | 24(15.4%) | 1.0 |
III–IV | 45(28.9%) | 14(9.0%) |
*Well-differentiation vs. Moderate differentiation+Poor differentiation.