Table 3. Univariate and multivariate Cox regression analyses of the prognostic variables in ESCC patients.

Variables	Subset	Hazard ratio	95% CI	P
Univariate analysis(n = 168)
Age	<60 vs. ≥60	1.390	(0.924–2.091)	0.114
Gender	Male vs. Female	0.472	(0.284–0.784)	0.004
T-stage	T1+T2 vs. T3+T4	2.326	(1.479–3.650)	0.000
N-stage	No vs. Yes	2.254	(1.533–3.313)	0.000
Histological grade	G1 vs. G2–G3	0.863	(0.652–1.142)	0.520
Clinical stage	I–II vs III–IV	2.741	(1.841–4.081)	0.000
14-3-3σ	Low vs. High	0.508	(0.316–0.816)	0.005
Multivariate analysis
Age	<60 vs. ≥60	1.199	(0.750–1.917)	0.449
Gender	Male vs. Female	0.658	(0.348–1.241)	0.196
T-stage	T1+T2 vs. T3+T4	2.577	(1.605–4.150)	0.000
N-stage	No vs. Yes	0.755	(0.167–3.418)	0.715
Histological grade	G1 vs. G2–G3	0.621	(0.323–1.195)	0.154
Clinical stage	I–II vs. III–IV	3.042	(0.679–13.635)	0.146
14-3-3σ	Low vs. High	0.466	(0.251–0.866)	0.016