Table 2. Correlation of STC1 or STC2 expression with clinicopathological variables in LSCC Patients (n = 152).
STC1, no. (%) | STC2, no. (%) | ||||||||
Variable | Cases | Negative | Low | High | P-value | Negative | Low | High | P-value |
Age (years) | 0.688 | 0.934 | |||||||
<65 | 93 | 31 (33.3) | 47 (50.5) | 15 (16.1) | 19 (20.4) | 48 (51.6) | 26 (28.0) | ||
>65 | 59 | 16 (27.1) | 35 (59.3) | 8 (13.6) | 12 (20.3) | 30 (50.8) | 17 (28.9) | ||
Type | 0.620 | 0.241 | |||||||
Glottic | 109 | 35 (32.1) | 58 (53.2) | 16 (14.7) | 25 (22.9) | 55 (50.5) | 29 (26.6) | ||
Supraglottic | 43 | 12 (27.9) | 24 (55.8) | 7 (16.3) | 6 (14.0) | 23 (53.5) | 14 (32.5) | ||
Thyroid-cartilage invasion | 0.086 | 0.013 | |||||||
No | 115 | 40 (34.8) | 59 (51.3) | 16 (13.9) | 27 (23.5) | 61 (53.0) | 27 (23.5) | ||
Yes | 37 | 7 (18.9) | 23 (62.2) | 7 (18.9) | 4 (10.8) | 17 (46.0) | 16 (43.2) | ||
T-Stage | 0.083 | 0.005 | |||||||
T1 and T2 | 88 | 31 (35.2) | 47 (53.4) | 10 (11.4) | 23 (26.1) | 47 (53.4) | 18 (20.5) | ||
T3 and T4 | 64 | 16 (25.0) | 35 (54.7) | 13 (20.3) | 8 (12.5) | 31 (48.4) | 25 (39.1) | ||
Lymphatic metastasis | 0.585 | 0.006 | |||||||
No | 116 | 38 (32.8) | 60 (51.7) | 18 (15.5) | 29 (25.0) | 59 (50.9) | 28 (24.1) | ||
Yes | 36 | 9 (25.0) | 22 (61.1) | 5 (13.9) | 2 (5.6) | 19 (52.8) | 15 (41.7) | ||
Clinical stage | 0.026 | <0.001 | |||||||
I and II | 81 | 30 (37.0) | 43 (53.1) | 8 (9.9) | 23 (28.4) | 43 (53.1) | 15 (18.5) | ||
III and IV | 71 | 17 (23.9) | 39 (54.9) | 15 (21.1) | 8 (11.3) | 35 (49.3) | 28 (39.4) | ||
Pathological differentiation | 0.698 | 0.043 | |||||||
Moderately and highly Differentiated | 123 | 38 (30.9) | 65 (52.8) | 20 (16.3) | 27 (22.0) | 66 (53.6) | 30 (24.4) | ||
Poorly differentiated | 29 | 9 (31.0) | 17 (58.6) | 3 (10.3) | 4 (13.8) | 12 (41.4) | 13 (44.8) |