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. 2014 Apr 17;9(4):e95466. doi: 10.1371/journal.pone.0095466

Table 3. Results of univariate and multivariate survival analyses for overall survival by the Cox proportional hazard model (n = 90).

Variable Categories RR (95%CI) P-value
Univariate survival analysis
Age (years) <65/>65 0.392 (0.143–1.080) 0.070
Type Glottic/Supraglottic 1.939 (0.803–4.681) 0.141
Thyroid-cartilage invasion No/Yes 4.942 (2.030–12.032) <0.001
T-Stage T1 and T2/T3 and T4 3.584 (1.301–9.873) 0.014
Lymphatic metastasis No/Yes 6.176 (2.453–15.545) <0.001
Clinical stage I and II/III and IV 5.925 (1.735–20.231) 0.005
Pathological differentiation Moderately and highly/Poorly differentiated 5.545 (2.269–13.548) <0.001
STC1 expression Negative/Low/High 1.048 (0.536–2.050) 0.890
STC2 expression Negative/Low/High 3.559 (1.694–7.479) 0.001
Multivariate survival analysis
Lymphatic metastasis No/Yes 3.064 (1.096–8.566) 0.033
Pathological differentiation Moderately and highly/Poorly differentiated 3.176 (1.219–8.269) 0.018
STC2 expression Negative/Low/High 2.477 (1.119–5.485) 0.025