Table 2. Brain regions with increased hypothalamic functional connectivity in migraine patients vs. healthy control subjects.

Brain Region	Lat.	z-stat	X	Y	Z	Vol (cm3)
Frontal
PrCG	R	3.0019	6	−32	72	0.35
MFG	R	2.8577	44	22	44	0.41
Parietal
SPL/SMG	L	2.8535	−46	−44	58	0.34
Temporal
ITG	L	3.7500	−50	0	−38	0.31
Planum Polare	R	3.6963	46	−4	−16	0.66
TmP	L	3.6501	−36	6	−22	0.41
MTG	L	3.1737	−58	−10	−26	0.46
	L	2.9026	−58	−12	−14	0.73
PHG	L	3.1445	−22	−16	−28	0.42
	L	2.8751	−22	−12	−34	0.33
STG	L	3.1319	−62	−30	0	0.76
Hippocampus	R	3.0327	44	−16	−24	0.3
	L	2.9341	−48	−22	−22	0.46
Sub-Cortical
Caudate	L	2.8124	−16	−4	24	0.5
Brainstem/Cerebellum
Nucleus coeruleus	R	3.4440	8	−34	−26	0.58
PN	L	3.5626	−8	−24	−42	0.59
	R	2.9397	8	−20	−40	0.79
	R	3.0793	6	−26	−42	0.54
Cerebellum
Cr I/II	L	3.3418	−40	−50	−48	0.85
V	L	3.2582	−12	−50	−14	0.78
	R	3.2184	14	−46	−16	0.52
	R	3.1642	12	−52	−20	1.19
	R	3.0691	6	−60	−22	0.86
	L	2.8326	−10	−60	−8	0.45
Verm VIIIa/VIIIb	L	3.2080	−2	−62	−36	0.33
Dentate nucleus	L	3.1411	−24	−50	−34	0.36
IX	R	3.0394	8	−46	−46	0.43
V/VI	R	2.8944	12	−58	−18	0.35

Legend: Cr I/II = Crus I and II; ITG = inferior temporal gyrus; IX = hemispheric lobule IX; MFG = middle frontal gyrus; PHG = parahippocampal gyrus; PN = pontine nuclei; PrCG = precentral gyrus; SMG = supramarginal gyrus; SPL = superior parietal lobule; STG = superior temporal gyrus; TmP = temporal pole; V = hemispheric lobule V; V/VI = hemispheric lobules V and VI; Verm VIIIa/VIIIb = Vermal lobules VIIIa/VIIIb.