Table 3. Comparative quantitative analysis of amino acid patterns at EXXR and CXG (FXXGXRXCXG) motifs in 12 fungal P450 families.
| P450 family | Number ofMember P450s | E-X-X-R | F-X-X-G-X-R-X-C-X-G |
| CYP52 | 93 | E-T(42)/V(24)-L(99)-R | F-N(85)-G(83)-G-P-R-I(79)-C-L(90)-G |
| CYP61 | 70 | E-T(26)/S(24)-L(90)-R | F(96)-G-S(34)/T(29)-G-P(91)-V(53)-C-L(61)-G(93) |
| CYP63 | 133 | E-T(74)-L(92)-R | F-N(78)-A(89)-G-P(98)-R(99)-I(87)-C-L(86)-G |
| CYP512 | 247 | E-S(62)-Q(53)-R | F(94)-G(99)-H(69)-G(99)-K(47)-H(87)-A(88)-C-P(95)-G |
| CYP5035 | 129 | E-T(54)-L(78)-R | F(98)-S(93)-F(31)/Y(29)-G(99)-P(94)-A(39)/M(23)-N(85)-V(81)-G(99) |
| CYP5037 | 261 | E-V(56)-L(48)/Y(20)-R | F(96)-G(99)-F(79)-G(99)-R(99.6)-I(38)/V(28)-C-P(90)-G(98) |
| CYP5136 | 68 | E-T(63)-L(61)-R | F-S(74)-A(76)-G-V(44)/L(19)-R(79)-G(49)/A(41)-C-I(79)-G |
| CYP5139 | 181 | E-T(62)-L(84)-R | F-L(40)/I(25)-G(62)-G-P(83)-R(83)-A(49)/S(16)-C-I(73)-G |
| CYP5141 | 86 | E-T(92)-L(95)-R | F-S(89)-A(35)/G(33)-G-P(47)/A(37)-R(93)-A(36)/G(30)-C-L(47)/I(45)-G |
| CYP5144 | 514 | E-V(29)/T(26)-L(58)-R(99.6) | F(97)-G(99)-F(68)-G(99)-R(99)-R(99.8)-I(65)-C-P(88)-G(99.8) |
| CYP5150 | 336 | E-T(94)-L(97)-R(99) | F(99)-L(49)/I(18)-G(77)-G(99)-G(40)/K(19)-R(85)-A(68)-C-I(90)-G |
| CYP5152 | 66 | E-V(30)/A(14)-L(38)/F(30)-R | F(59)-G-F-G-R(98)-R-V(66)-C-P(77)-G |
The percentage predominance of amino acids at particular positions is calculated considering the total number of amino acids as 100%. Amino acids or patterns of amino acids contributing more than 50% at the specific position are shown in the table. Amino acids conserved (100%) at the specific position(s) are represented by their symbol. The numerical values in the table are percentage values.