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. 2014 Feb 11;155(5):1793–1805. doi: 10.1210/en.2013-2086

Figure 4.

Figure 4.

Organ size relative to body weight and liver TG content. Organ weights were measured at 6 months of age in male (A) and female (E) control (white bars; n = 15–16/group per sex) and LiGHRKO (black bars; n = 15–16/group per sex) mice and are reported relative to body weight. Liver, skeletal muscle (gastrocnemius, quadriceps), heart, WAT (sc, perigonadal, retroperitoneal, mesenteric), BAT, kidney, spleen, lung, and brain weights are shown (A and E). Liver TG content was determined in hepatic tissue from male (B) and female (F) LiGHRKO and control mice (n = 15–16/group per sex). H&E staining was also performed on hepatic tissue from male (C and D) and female (G and H) control and LiGHRKO mice, respectively. Values in A, B, E, and F are represented as mean ± SEM (n = 15–16/group per sex). *, P < .05; LiGHRKO (FFCx) vs control (FFxx). Gast, gastrocnemius; Quad, quadriceps; SubQ, sc; peri, perigonadal; retro, retroperitoneal; Mes, mesenteric.