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. 2014 Feb 24;155(5):1700–1707. doi: 10.1210/en.2013-1846

Figure 1.

Figure 1.

Effect of CCK and Apo AIV on ability to control food intake. Food intake was determined in fasted rats after receiving one of the following treatments. A, Intraperitoneal injection of either CCK-8 or saline (SAL). B, i4vt administration of Apo AIV or CSF. C, Two injections of CCK ip, Apo AIV i4vt, or vehicles (CSF or SAL). D, Two combined doses of CCK ip, Apo AIV i4vt, or vehicles at 24 hours. E, Two i4vt injections of Apo AIV (4 μg), lorglumide (Lorg) (3 μg), or vehicles. F, Three combinations of CCK (0.25 μg/kg), Apo AIV (4 μg), and Lorg (3 μg). Data are expressed as mean ± SEM, n = 10, values with asterisks represent significant differences relative to the vehicle-treated group (P < .05). BW, body weight.