. 2014 Feb 19;5(4):253–260. doi: 10.1021/cn5000056

Table 1. Recombinant Receptor Binding and Potentiation of Cl^– Ion Current in Cells.

receptor subtype	K_i (nM)^a	EC₅₀ (nM)^b	max potentiation^b
α₁β₁γ₂	16	53	120%
α₁β₂γ₂	16
α₁β₃γ₂	13
α₁β₂γ₃	670
α₂β₁γ₂	17	60	270%
α₂β₂γ₂	17
α₃β₁γ₂	17	140	400%
α₃β₂γ₂	8.6
α₃β₃γ₂	33
α₄β₂γ₂	>10 000
α₅β₁γ₂	–	4000	110%
α₅β₂γ₂	15
α₅β₃γ₂	17
α₆β₃γ₂	>10 000

K_i data from various sources as compiled in ref (40).

GABA evoked Cl^– ion current in HEK293 cells expressing transfected receptors. Data from ref (42).

Table 1. Recombinant Receptor Binding and Potentiation of Cl– Ion Current in Cells.