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. 2014 Jan 31;5(4):305–317. doi: 10.1021/cn4002329

Table 3. Binding Parameters for Quenching of P-gp Trp Fluorescence by Binding of QT and QT Dimersa.

compd ΔFmax (%) Kd (μM)
QT 65 ± 2.7 29 ± 2.9
QT2C2 (1) 45 ± 0.8 1.5 ± 0.1
QT2C2Me2 (8) 43 ± 0.9 1.0 ± 0.1
a

Kd values were estimated by fitting of the quenching data from 3 independent experiments, and represents the mean ± fitting error.