. 2014 Jan 31;5(4):305–317. doi: 10.1021/cn4002329

Table 4. Inhibition of P-gp-Mediated Transport in Reconstituted Proteoliposomes by QT and the Dimer QT₂C₂Me₂ (8).

	IC₅₀ for inhibition of transport (μM)^a
compd	TMR	H33342	LDS-751
QT	59 ± 9	42.5 ± 1.5	83.6 ± 1.6
QT₂C₂Me₂ (8)	21 ± 1	18.1 ± 7.2	36.3 ± 0.1

IC₅₀ values were determined from inhibition plots as shown in Figure 4 and represent the mean ± range for two independent experiments.

Table 4. Inhibition of P-gp-Mediated Transport in Reconstituted Proteoliposomes by QT and the Dimer QT2C2Me2 (8).