Table 2.
Relationship between hormone levels and subsequent recognition memory | ||||||
Predictor |
Unadjusted |
Adjusted |
||||
βa | R2b | βa | βcassay round | R2b | ||
BDNF | −0.215* (0.109) | 0.059 (0.045) | −0.200 (0.107) | −0.188 (0.106) | 0.103 (0.034) | |
Cortisol | −0.145 (0.111) | 0.026 (0.009) | −0.166 (0.107) | −0.243* (0.107) | 0.100 (0.001) | |
IGF-1 | 0.063 (0.113) | 0.005 (−0.011) | 0.065 (0.110) | −0.213 (0.110) | 0.062 (−0.026) | |
VEGF | −0.003 (0.115) | 0.000 (−0.017) | 0.048 (0.115) | −0.219 (0.115) | 0.056 (0.025) | |
Relationship between aerobic fitness and subsequent recognition memory | ||||||
Predictor |
Unadjusted |
Adjusted |
||||
βafitness | R2b | βafitness | βcsex | βRER ≥ 1.15 | R2b | |
Fitness | −0.002 (0.112) | 0.000 (−0.016) | 0.008 (0.118) | −0.086 (0.125) | 0.128 (0.121) | 0.020 (−0.029) |
Interaction between BDNF and aerobic fitness on subsequent recognition memory | ||||||
βBDNF· fitness | βaBDNF | βafitness | βcsex | βRER ≥ 1.15 | βcassay round | R2b |
0.609** (0.228) | −0.294** (0.109) | −0.059 (0.105) | -- | -- | -- | 0.157 (0.117) |
0.587** (0.222) | −0.252* (0.106) | 0.040 (0.118) | −0.066 (0.116) | 0.181 (0.113) | −0.262* (0.113) | 0.232 (0.158) |
This table presents a series of beta regression models with and without adjusting for confounding covariates; each row corresponds to a different model predicting SMT accuracy. Coefficients are presented as β (SEβ). Exponentiated coefficients can be interpreted as odds-ratios
Continuous input variables were standardized prior to model estimation (see Methods for details)
Beta regression pseudo-R2 (ordinary least squares regression adjusted-R2for comparison)
Positive values on the coefficient for assay round reflect higher outcomes for assay wave two; positive values on the coefficient for sex reflect higher outcomes for male subjects
P < 0.05
P < 0.01
P < 0.001