Table 2.
Patients with respiratory symptoms (AERD) | |||
---|---|---|---|
Hour | Day 1 | Day 2 | Day 3 |
08:00 | Placebo | ASA 3 or 30 mg | ASA 150 mg |
11:00 | Placebo | ASA 60 mg | ASA 325 mg |
14:00 | Placebo | ASA 100 mg | ASA 650 mg |
Monitor pulmonary function, naso-ocular symptoms/signs | |||
Test positive if a decrease of FEV1 ° 20 % is observed | |||
Patients with urticaria and/or angioedema | |||
08:00 | Placebo | ASA 100 mg | ASA 325 mg |
10:00 | Placebo | ASA 200 mg | ASA 650 mg |
Skin scores recorded every 2 hours |