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. 2010 Jan 19;3(1):188–224. doi: 10.3390/ph3010188

Table 2.

A selected pharmacological profile of adaptogens, clinical efficacy in humans relative to CNS.

Pathophysiological condition Rhodiola Eleutherococcus Schisandra
Neuro-endocrine system Physical fatigue + + ++
Mental fatigue (declined attention) ++ + +
Stress induced chronic fatigue + +
Depression +