Table 2. Metabolite uptake and excretion in the culture media.
Cell | Metabolite | Undifferentiated | Differentiated | Change | p value |
---|---|---|---|---|---|
Uptake | Leucine | 0.48 ± 0.04 | 0.99 ± 0.03 | ↑2.06 | 0.001 |
Iso-leucine | 0.46 ± 0.04 | 0.87 ± 0.09 | ↑1.89 | 0.001 | |
Valine | 0.24 ± 0.05 | 0.40 ± 0.04 | ↑1.66 | 0.02 | |
Glutamine | 2.93 ± 0.05 | 3.32 ± 0.28 | ↑1.13 | 0.05 | |
Histidine | 0.08 ± 0.02 | 0.08 ± 0.03 | 0.47 | ||
Tyrosine | 0.10 ± 0.01 | 0.35 ± 0.07 | ↑3.5 | 0.008 | |
Phenylalanine | 0.13 ± 0.01 | 0.29 ± 0.01 | ↑2.23 | 0.03 | |
Glucose | 6.91 ± 0.60 | 8.81 ± 0.39 | ↑1.27 | 0.03 | |
Excretion | Lactate | 31.44 ± 3.54 | 16.88 ± 0.82 | 0.23 | |
Alanine | 0.58 ± 0.10 | 0.35 ± 0.07 | ↓1.65 | 0.04 |