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. Author manuscript; available in PMC: 2014 Apr 18.
Published in final edited form as: Nanomedicine (Lond). 2012 Jul 26;7(11):1697–1711. doi: 10.2217/nnm.12.65

Figure 4. Superparamagnetic iron oxide nanoparticle localization in mice.

Figure 4

Mouse livers and spleens were ‘stained’ with the Perls’ Prussian blue reaction, which indicates iron deposition. (A) Liver low-dose superparamagnetic iron oxide nanoparticles with high-field alternating magnetic field exposure treatment group; (B) liver high-dose superparamagnetic iron oxide nanoparticles with high-field alternating magnetic field exposure treatment group; (C) spleen low-dose superparamagnetic iron oxide nanoparticles with high-field alternating magnetic field exposure treatment group; (D) spleen high-dose superparamagnetic iron oxide nanoparticles with high-field alternating magnetic field exposure treatment group. Arrows indicate necrosis.