. Author manuscript; available in PMC: 2014 Apr 18.

Published in final edited form as: Nanomedicine (Lond). 2012 Jul 26;7(11):1697–1711. doi: 10.2217/nnm.12.65

Table 4.

Iron deposition scores in the liver and spleen.

Group	Liver (Prussian blue)	Spleen (Prussian blue)
S0	0	0
SH	0	0
LL	1	1
LH	1	1.33
H0	2	2.5
HL	2	2
HH	2.67	2

Slides were prepared and stained with hematoxylin and eosin, and were examined by two pathologists and evaluated for necrosis and pigment. Semiquantitative scoring ranged from 0 to 4, with 0 indicating no observable pigment and 4 indicating highest pigment deposition. The first letter of each group designation indicates the dose of nanoparticles injected: saline (S), low-dose (L) or high-dose (H) superparamagnetic iron oxide. The second letter of each group designation indicates the field strength for alternating magnetic field exposure: zero (0), low (L) or high (H) field.