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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Eur J Cancer. 2013 Nov 15;50(2):302–308. doi: 10.1016/j.ejca.2013.10.006

Table 4.

Response and Survival by Rash

P
Grade Complete
Response		 Partial
Response		 Stable
Disease		 Progression Unevaluable ORR DCR
Grade <2 N 0 2 16 25 14 0.68 0.14
% 0.0 3.5 28.1 43.9 24.5
Grade ≥2 N 2 2 24 23 11
% 3.2 3.2 38.7 37.1 17.8
Efficacy Landmark Skin Rash # of
Events/N		 Median
(months)		 95% CI P
OS 2-Month Grade <2 41/43 3.9 (2.8, 6.6) 0.02
Grade ≥2 54/58 10.7 (6.5, 19.6)
4-Month Grade <2 33/35 3.9 (1.6, 9.3) 0.01
Grade ≥2 48/52 15.7 (8.4, 21.2)