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Scanning electron micrographs of the intact sinusoid and the fenestrated endothelium. DOI induced changes in fenestration size in young, but not in old, animals. (A) 7-mo untreated control, (B) 24-mo untreated control, (C) 7-mo DOI treated, and (D) 24-mo DOI treated. DOI = 2,5-dimethoxy-4-iodoamphetamine.
