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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2013 Nov 16;1842(2):220–231. doi: 10.1016/j.bbadis.2013.11.009

Figure 2.

Figure 2

Abnormal mitochondrial morphology in AD cybrid cells. Cybrid cells were labeled with Mitotracker Red for visualization of mitochondrial morphology. (A1–A3) Quantitative measurement of mitochondrial density presented as the percentage of area occupied by mitochondria in entire cells (A1), neuronal process (A2), or cell body (A3), using NIH Image J software. B) Representative images of Mitotracker Red staining. Lower panels present larger images corresponding to the indicated images above. Scale bar = 5 µm. (C1–C3) Average mitochondrial length over the entire cell, neuronal processes, and cell body was lower in AD cybrid cells compared to non-AD cells. (C4) Quantification of mitochondrial sizes based on the grouped differently sized bins. N = 7 cell lines/group. * p<0.05 versus non-AD group.