Table 1.
Gene Set Analysis results showing the relative shift from controls (score) and significance of custom pathways targeting olfactory signal transduction (OST) at each chlorpyrifos or mixture treatment. Significant pathways (p<0.05) are colored green or red. Negative shifts in the treated datasets relative to controls are indicated in green. Positive shifts are in red.
Gene set number | Gene set name | Gene set length | Score | p-value | Score | p-value |
---|---|---|---|---|---|---|
| ||||||
CPF L | CPF L | Mix A | Mix A | |||
| ||||||
1792 | OST110 Pathway | 110 | -0.23 | 0.14 | -0.51 | 0.05 |
1791 | OST60 Pathway | 60 | -0.20 | 0.19 | -0.23 | 0.16 |
1790 | OST40 Pathway | 40 | -0.12 | 0.29 | -0.45 | 0.10 |
1789 | OST21 Pathway | 21 | 0.29 | 0.10 | -0.42 | 0.03 |
1788 | OST16 Pathway | 16 | 0.08 | 0.41 | 0.25 | 0.21 |
1787 | OST12 Pathway | 12 | 0.14 | 0.31 | 0.33 | <0.001 |
1794 | OSTroot Pathway | 18 | -0.37 | 0.04 | -0.86 | <0.001 |
1793 | OSTinhib Pathway | 31 | -0.10 | 0.24 | -0.14 | 0.31 |
| ||||||
CPF M | CPF M | Mix B | Mix B | |||
| ||||||
1792 | OST110 Pathway | 110 | -0.12 | 0.20 | -0.63 | <0.001 |
1791 | OST60 Pathway | 60 | -0.09 | 0.34 | -0.37 | 0.05 |
1790 | OST40 Pathway | 40 | -0.01 | 0.44 | -0.67 | <0.001 |
1789 | OST21 Pathway | 21 | 0.02 | 0.47 | -0.47 | <0.001 |
1788 | OST16 Pathway | 16 | -0.05 | 0.41 | 0.03 | 0.45 |
1787 | OST12 Pathway | 12 | -0.13 | 0.32 | -0.16 | 0.29 |
1794 | OSTroot Pathway | 18 | -0.10 | 0.20 | -1.05 | <0.001 |
1793 | OSTinhib Pathway | 31 | 0.01 | 0.45 | 0.17 | 0.40 |
| ||||||
CPF H | CPF H | Mix C | Mix C | |||
| ||||||
1792 | OST110 Pathway | 110 | -0.14 | 0.19 | -0.70 | <0.001 |
1791 | OST60 Pathway | 60 | -0.04 | 0.35 | -0.51 | <0.001 |
1790 | OST40 Pathway | 40 | -0.05 | 0.40 | -0.87 | <0.001 |
1789 | OST21 Pathway | 21 | -0.46 | <0.001 | -0.68 | <0.001 |
1788 | OST16 Pathway | 16 | -0.25 | 0.26 | -0.03 | 0.44 |
1787 | OST12 Pathway | 12 | -0.33 | 0.05 | -0.08 | 0.40 |
1794 | OSTroot Pathway | 18 | -0.14 | 0.36 | -1.55 | <0.001 |
1793 | OSTinhib Pathway | 31 | -0.06 | 0.44 | 0.15 | 0.31 |