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. Author manuscript; available in PMC: 2014 Apr 18.
Published in final edited form as: Aquat Toxicol. 2011 Feb 2;102(0):205–215. doi: 10.1016/j.aquatox.2011.01.012

Table 1.

Gene Set Analysis results showing the relative shift from controls (score) and significance of custom pathways targeting olfactory signal transduction (OST) at each chlorpyrifos or mixture treatment. Significant pathways (p<0.05) are colored green or red. Negative shifts in the treated datasets relative to controls are indicated in green. Positive shifts are in red.

Gene set number Gene set name Gene set length Score p-value Score p-value

CPF L CPF L Mix A Mix A

1792 OST110 Pathway 110 -0.23 0.14 -0.51 0.05
1791 OST60 Pathway 60 -0.20 0.19 -0.23 0.16
1790 OST40 Pathway 40 -0.12 0.29 -0.45 0.10
1789 OST21 Pathway 21 0.29 0.10 -0.42 0.03
1788 OST16 Pathway 16 0.08 0.41 0.25 0.21
1787 OST12 Pathway 12 0.14 0.31 0.33 <0.001
1794 OSTroot Pathway 18 -0.37 0.04 -0.86 <0.001
1793 OSTinhib Pathway 31 -0.10 0.24 -0.14 0.31

CPF M CPF M Mix B Mix B

1792 OST110 Pathway 110 -0.12 0.20 -0.63 <0.001
1791 OST60 Pathway 60 -0.09 0.34 -0.37 0.05
1790 OST40 Pathway 40 -0.01 0.44 -0.67 <0.001
1789 OST21 Pathway 21 0.02 0.47 -0.47 <0.001
1788 OST16 Pathway 16 -0.05 0.41 0.03 0.45
1787 OST12 Pathway 12 -0.13 0.32 -0.16 0.29
1794 OSTroot Pathway 18 -0.10 0.20 -1.05 <0.001
1793 OSTinhib Pathway 31 0.01 0.45 0.17 0.40

CPF H CPF H Mix C Mix C

1792 OST110 Pathway 110 -0.14 0.19 -0.70 <0.001
1791 OST60 Pathway 60 -0.04 0.35 -0.51 <0.001
1790 OST40 Pathway 40 -0.05 0.40 -0.87 <0.001
1789 OST21 Pathway 21 -0.46 <0.001 -0.68 <0.001
1788 OST16 Pathway 16 -0.25 0.26 -0.03 0.44
1787 OST12 Pathway 12 -0.33 0.05 -0.08 0.40
1794 OSTroot Pathway 18 -0.14 0.36 -1.55 <0.001
1793 OSTinhib Pathway 31 -0.06 0.44 0.15 0.31