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. 2014 Mar 4;7(5):1116–1122. doi: 10.3892/etm.2014.1598

Figure 4.

Figure 4

Effect of icariin on apoptosis. (A) Representative images and (B) quantitative results demonstrating that 10 μM icariin attenuated cell apoptosis following stimulation with Ang II for 48 h, as shown by TUNEL staining. (C) Representative blots and (D) quantitative results demonstrating that 10 μM icariin decreased the protein expression levels of Bax and cleaved-caspase 3, but increases the expression levels of Bcl-2 in response to Ang II stimulation. *P<0.05, vs. control; #P<0.05, vs. Ang II-treated cells. Ang II, angiotensin II; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling.