Table 1. Genes involved with Parkinsonian Syndrome.
PARK loci | Gene | Gene Locus | Inheritance Pattern |
---|---|---|---|
PARK1/PARK4 | SNCA (alpha-synuclein) | 4q21 | Autosomal dominant |
PARK8 | LRRK2 (Leucine-rich repeat kinase 2) | 12q12 | Autosomal dominant |
PARK2 | Parkin | 6q25–q27 | Autosomal recessive |
PARK6 | PINK1 (PTEN-induced putative kinase 1) | 1p35–p36 | Autosomal recessive |
PARK7 | DJ-1 | 1p36 | Autosomal recessive |
PARK9 | ATP13A2 | 1p36 | Autosomal recessive |