Table 2. Comparison of MRI devices and results on cardiac function in small animals and in humans.
Tesla | gradient | TR/TE in ms | Flip angle | FOV | spatial resolution | species | Model | n per group | Control groups | EF of controls in % | mean relative SD EDV/ESV/SV (%) | mean relative SD of LVEF (%) | |
Grabmaier et al. | 1.5 | 30 mT/m | 18/6.5 | 30° | 35 mm | 220×220×1000 µm | SWR/J | DCM | (4)7–22 | y | 52.0±7.7 | 23.5/26.5/23.6 | 13.1; 14.8* |
Nindl et al. | 9.4 | 400 mT/m | 50.5/1.8 | - | 25×25 mm2 | 98×98×98 µm | BALB/c | DCM | 6–7 | n | 62.8±2.0; 63.0±1.3 | 6.0/9.6/5.8 | 2.9; 2.6* |
Cochet et al. | 9.4 | 950 mT/m | 4.3/1.1 | 20° | 11×17×2 mm | 133×133×133 µm | C57Bl/6 | HCM | 15 | n | - | 10.0/17.9/- | 0.1 |
Stuckey et al. | 11.7 | - | 4.6/1.4 | 17.5° | 25.6×25.6 | 100×100×1000 µm | mdx mouse | mdx mouse | 10–12 | y | 65±2; 60±2; | 6.1/9.5/6.0 | 3.7 |
model | model of | 65±2; 60±3; | 3.6* | ||||||||||
// | muscular | 59±2 | |||||||||||
C57Blk10 | dystrophy | ||||||||||||
Protti et al. | 7 | - | - | - | - | - | C57Bl/6J | LAD ligation | - | n | 65.6±4.3 | 20.5/27.3/28.0 | 6.6 |
Klem et al. # | 1.5 | - | - | - | - | - | human | ICM | 100–906 | n | - | - | 34.4 |
Gardner et al. # | 1.5 | - | - | 45° | 35×35 cm | 2.2×1.3×1.3 mm | human | ICM | 30–47 | y | - | - | 15.4; 9.2* |
= LVEF evaluation in human populations;
y = yes, n = no; SD = standard deviation;
* = mean relative SD in % of LVEF of the control group only.