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. 2014 Apr 18;9(4):e94615. doi: 10.1371/journal.pone.0094615

Table 2. Comparison of MRI devices and results on cardiac function in small animals and in humans.

Tesla gradient TR/TE in ms Flip angle FOV spatial resolution species Model n per group Control groups EF of controls in % mean relative SD EDV/ESV/SV (%) mean relative SD of LVEF (%)
Grabmaier et al. 1.5 30 mT/m 18/6.5 30° 35 mm 220×220×1000 µm SWR/J DCM (4)7–22 y 52.0±7.7 23.5/26.5/23.6 13.1; 14.8*
Nindl et al. 9.4 400 mT/m 50.5/1.8 - 25×25 mm2 98×98×98 µm BALB/c DCM 6–7 n 62.8±2.0; 63.0±1.3 6.0/9.6/5.8 2.9; 2.6*
Cochet et al. 9.4 950 mT/m 4.3/1.1 20° 11×17×2 mm 133×133×133 µm C57Bl/6 HCM 15 n - 10.0/17.9/- 0.1
Stuckey et al. 11.7 - 4.6/1.4 17.5° 25.6×25.6 100×100×1000 µm mdx mouse mdx mouse 10–12 y 65±2; 60±2; 6.1/9.5/6.0 3.7
model model of 65±2; 60±3; 3.6*
// muscular 59±2
C57Blk10 dystrophy
Protti et al. 7 - - - - - C57Bl/6J LAD ligation - n 65.6±4.3 20.5/27.3/28.0 6.6
Klem et al. # 1.5 - - - - - human ICM 100–906 n - - 34.4
Gardner et al. # 1.5 - - 45° 35×35 cm 2.2×1.3×1.3 mm human ICM 30–47 y - - 15.4; 9.2*
#

 = LVEF evaluation in human populations;

y = yes, n = no; SD = standard deviation;

* = mean relative SD in % of LVEF of the control group only.