Table 1. General characteristics of patients.
mRS>2 (N = 130) | mRS 0–2 (N = 77) | p | Alive (N = 174) | Death (N = 33) | P | |
Age (mean±SD) | 73.42±9.72 | 65.83±11.72 | <0.001 | 69.37±10.92 | 77.03±9.94 | <0.001 |
Male (n, %) | 77 (59.2) | 50 (64.9) | 0.462 | 109 (62.6) | 18 (54.5) | 0.437 |
Risk factors | ||||||
HTN | 88 (67.7) | 45 (58.4) | 0.230 | 107 (61.5) | 26 (78.8) | 0.074 |
DM | 29 (22.3) | 15 (19.5) | 0.726 | 35 (20.1) | 9 (27.3) | 0.359 |
Dyslipidemia | 8 (6.2) | 9 (11.7) | 0.193 | 15 (8.6) | 2 (6.1) | >0.999 |
AF | 48 (36.9) | 17 (22.1) | 0.030 | 44 (25.3) | 21 (63.6) | <0.001 |
CAD | 12 (9.2) | 5 (6.5) | 0.605 | 11 (6.3) | 6 (18.2) | 0.035 |
Previous stroke | 12 (9.2) | 10 (13.0) | 0.485 | 16 (9.2) | 6 (18.2) | 0.131 |
Smoking | 45 (34.6) | 35 (45.5) | 0.141 | 72 (41.4) | 8 (24.4) | 0.079 |
NIHSS (med, IQR) | 12.0 (7.0) | 7.0 (4.50) | <0.001 | 9.0 (8.0) | 13.0 (5.50) | 0.003 |
Onset to IVT time (mean±SD) | 129.91±55.38 | 130.54±50.70 | 0.935 | 128.70±52.66 | 137.75±58.35 | 0.375 |
TOAST | 0.802 | 0.846 | ||||
LAA | 32 (24.6) | 29 (37.7) | 58 (33.3) | 3 (9.1) | ||
CE | 65 (50.0) | 32 (29.9) | 65 (37.4) | 23 (69.7) | ||
SVO | 2 (1.5) | 2 (2.6) | 4 (2.3) | 0 | ||
OE | 1 (0.8) | 1 (1.3) | 2 (1.1) | 0 | ||
UD | 30 (23.1) | 22 (28.6) | 45 (25.9) | 7 (21.2) | ||
Initial SBP | 140.23±22.08 | 141.31±27.14 | 0.755 | 138.43±24.00 | 152.12±20.88 | 0.003 |
BG parameters | ||||||
BG before IVT | 134.73±40.47 | 130.12±47.93 | 0.473 | 130.48±42.71 | 145.81±44.53 | 0.063 |
BG after IVT | 144.88±42.21 | 118.42±33.17 | <0.001 | 129.84±37.07 | 162.75±49.88 | <0.001 |
Mean BG | 139.04±36.66 | 120.55±29.90 | <0.001 | 12779±31.73 | 155.19±44.35 | <0.001 |
Max BG | 164.20±53.20 | 147.72±48.29 | 0.027 | 151.93±45.50 | 190.42±69.86 | 0.004 |
SD of BG | 21.27±17.19 | 22.16±17.52 | 0.712 | 20.05±14.99 | 29.70±25.00 | 0.003 |
SD of mean BG | 0.14±0.08 | 0.17±0.11 | 0.034 | 0.15±0.09 | 0.17±0.12 | 0.161 |
Severe WMH | 46 (35.4) | 15 (19.5) | 0.018 | 46 (26.4) | 15 (45.5) | 0.037 |
Microbleeds | 14 (10.8) | 9 (11.7) | 0.823 | 19 (10.9) | 4 (12.1) | 0.768 |
HTN, hypertension; DM, diabetes mellitus; AF, atrial fibrillation; CAD, coronary artery disease; NIHSS, National Institutes of Health Stroke Scale; IVT, intra-venous thrombolysis; SD, standard deviation; TOAST, Trials of Organization; BP, blood pressure; BG, blood glucose; SD, standard deviation; WMH, white matter hyperintensity.