Table 1. ROSSINI trial: unit costs at 2011 value.

Resource	Unit cost (£)	Source
WEPD (intervention)	15	Manufacturer [13]
HOSPITAL CARE
Day on general ward	311	NHS Reference Costs 2010/2011 [14]
Day in ITU	1515	NHS Reference Costs 2007/2008* [15]
Day in HDU	856	NHS Reference Costs 2007/2008* [15]
PRIMARY CARE
GP visit	36	Curtis 2011 [16]
Practice nurse visit	13	Curtis 2011 [16]
District nurse visit	73	Curtis 2011 [16]
Outpatient clinic visit	101	NHS Reference Costs 2010/2011 [14]
Medication	as appropriate	British National Formulary 2011 [17]

*The costs for a day in Intensive Therapy Unit (ITU) and a day in High Dependency Unit (HDU) were not available in NHS Reference Costs 2010/2011. The last available document where they were given explicitly was the 2007/2008 edition. For the purpose of this analysis, the 2007/2008 unit costs were updated to their 2011 value using the appropriate Hospital and community health services (HCHS) pay and price inflation (Curtis 2011).