Table 5. ROSSINI trial economic evaluation: summary of incremental costs and incremental QALYs across the analysed scenarios.

Scenario	Variable	Mean difference(WEPD – standard care)	95% BCa CI	ICER
Base-case unadjusted	Total cost (£)	290	−372 to 949	WEPD is dominated
	QALY	−0.00002	−0.0018 to 0.0017
Base-case adjusted	Total cost (£)	311	−273 to 1012	1,712 k/QALY
	QALY	0.0002	−0.0015 to 0.0019
Complete case unadjusted	Total cost (£)	237	−407 to 892	740 k/QALY
	QALY	0.0003	−0.0023 to 0.0016
Complete case adjusted	Total cost (£)	369	−214 to 976	WEPD is dominated
	QALY	−0.0001	−0.0022 to 0.0019