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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Feb 6;34(5):996–1001. doi: 10.1161/ATVBAHA.113.303113

Figure 3. Platelet/neutrophil and platelet/monocyte interactions following CLP.

Figure 3

(A) Twenty four hours after CLP, whole blood from wild-type and hIL-4R/Ibα mice was analyzed via flow cytometry to determine GP Ib-IX mediated platelet-neutrophil or platelet/monocyte events. (B) The percentage of neutrophils bound by platelets is reduced following CLP in both animal strains relative to static conditions. (C) A similar trend was observed in the monocyte gate with an overall reduction in platelet associated events following CLP. Despite the overall reduction in of platelet associated events in both gates, wild type samples did retain elevated interactions with platelets for both the neutrophil (p = 0.04) and monocyte (p = 0.05) populations. N = 6 (Normal) N = 11 (24 hrs post-CLP).