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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Feb 6;34(5):996–1001. doi: 10.1161/ATVBAHA.113.303113

Figure 5. Inflammatory cytokine and chemokine levels 24 hours post-CLP.

Figure 5

Serum levels of 25 different inflammatory mediators were assessed following CLP surgery. Serum collected from mice was analyzed on an individual basis. A total of six different analytes (including TNFα, not shown) secreted primarily by cells of monocyte/macrophage lineage had significantly different concentrations when comparing wild-type and hIL-4R/Ibα serum. Four of the five analytes showed elevated levels in the hIL-4R/Ibα samples; MIP-1β (p = 0.0078), MCP-1 (p = 0.0129), KC (p = 0.0054) and IL-6 (p = 0.0085). Serum levels of IL-15 was reversed with the wild-type strain exhibiting higher serum levels (p = 0.0006). A horizontal bar indicates overall mean. N = 10 for each group.