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Modified NIH consensus criteria for GISTs risk stratification (adapted from[7])
| Risk category | Tumor size (cm) | Mitotic index (per 50 high power fields) | Primary tumor site |
|---|---|---|---|
| Very low risk |
<2.0 |
≤5 |
Any |
| Low risk |
2.1 to 5.0 |
≤5 |
Any |
| Intermediate risk |
2.1 to 5.0 |
>5 |
Gastric |
| <5.0 |
6-10 |
Any |
|
| 5.1 to 10.0 |
≤5 |
Gastric |
|
| High risk | Any |
Any |
Tumor rupture |
| >10 cm |
Any |
Any |
|
| Any |
>10 |
Any |
|
| >5.0 |
>5 |
Any |
|
| 2.1 to 5.0 |
>5 |
Non-gastric |
|
| 5.1 to 10.0 | ≤5 | Non-gastric |
