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. 2014 Apr 8;14:68. doi: 10.1186/1471-230X-14-68

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Copyright © 2014 Matsumoto et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The time course of clinical changes of 3% dextran sulfate sodium (DSS) colitis with/without lentivirus vector (LV) encoding mouse interleukin 10 (mIL-10). Mice were treated with 3% DSS from Days 1–7 and 18–24. Four treatment groups (n = 8 mice per group) were (i) a control group who did not receive DSS or an LV (NC), (ii) a group who received DSS + a mock plasmid control (mock), (iii) a group who received DSS + a single dose of the mIL-10 LV on Day 3 (LV(1)), and (iv) a group who received DSS + doses of the mIL-10 LV on Days 3 and 20 (LV(2)).