Table 1.

Summary of the Clinical Characteristics of Family Members with the IL-20R2 T104M Mutation

			Cup to disc ratio		Central corneal thickness		Maximum IOP
Individual no.	Age at diagnosis or exam	Diagnosis	OD	OS	OD	OS	OD	OS	Visual field	Surgery
93001	48	POAG	0.9	0.9	0.552	NA	26	46	Severe loss OU	Trabeculectomy OU
94099	58	POAG	0.7	0.4	0.578	0.568	21	28	Superior loss OD	Trabeculectomy OU
93005	38	POAG	0.7	0.7	0.544	0.550	28	24	Nasal step OS	None
93010	68	POAG	0.9	0.9	0.527	0.517	24	25	Superior loss OD	None
93012	57	POAG	0.7	0.6	0.572	0.592	22	23	Nasal step OU	None
93016	50	POAG	0.9	0.9	NA	NA	22	22	NA	Laser trabeculoplasty OU
94004	60	POAG	0.7	0.6	NA	NA	26	24	NA	None
94010	47	POAG	0.7	0.8	0.608	0.580	24	24	Nasal step OS	None
94024	55	POAG	0.5	0.7	0.599	0.594	21	25	Nasal step OS	None
94025	80	POAG	0.5	0.9	NA	NA	35	36	NA	Laser trabeculoplasty OS
02004a	55	POAG	0.9	0.9	NA	NA	35	26	Severe loss OU	Trabeculectomy OU
04025	24	Suspect	0.3	0.3	0.590	0.590	32	25	NA	None
93011	58	Suspect	0.4	0.4	0.604	0.593	23	23	Normal	None
94075	32	Suspect	0.5	0.5	0.532	0.544	18	17	NA	None
94023	66	Suspect	0.5	0.5	0.532	0.533	18	18	NA	None
94013	39	Suspect	0.4	0.4	0.566	0.572	20	20	NA	None
94002	56	Normal	0.3	0.3	0.543	0.547	19	18	NA	None
94019	16	Normal	0.3	0.3	0.552	0.543	16	16	NA	None
05040	19	Normal	0.2	0.2	0.544	0.554	20	20	NA	None
05041	17	Normal	0.2	0.2	0.551	0.540	20	20	NA	None
93013	74	Normal	0.3	0.3	0.626	0.650	17	18	NA	None

^aNo DNA is available; the genotype of this individual is inferred from her daughter and granddaughter's status.

IL-20R, interleukin-20 receptor; POAG, primary open angle glaucoma; IOP, intraocular pressure; OD, oculus dexter; OS, oculus sinister; OU, oculus uterque.