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Venn maps of genes of the trabecular meshwork altered by overexpression of wild-type and 4 glaucoma-causative myocilin mutants. Hybridization was conducted on Affymetrix GeneChips (n=17) and analyzed with GeneSpring 10 software. Nonredundant gene lists had cutoff fold-change values of≥and ≤1.5. (A) Number of genes altered in each of the mutants that overlap with genes altered by the wild-type. (B) Number of genes altered in all mutants.6
