FIG. 1.

Comparison of outflow facility in bovine, monkey, and human eyes. Percent change in outflow facility in bovine, monkey, and human eyes after Y-27632 treatment (50 μM). Human eyes required a longer perfusion time (3 h) with Y-27632 to achieve a similar percent increase in outflow facility as found in bovine eyes when perfused for a short duration (30 min), whereas this increase was still less than the level achieved in monkey eyes when perfused for the same duration (30 min) with Y-27632 (from Yang et al.²⁵).