FIG. 2.

Light microscopic analysis in bovine and monkey eyes. (A) An image from a control bovine eye, no separation was found between the inner wall of the aqueous plexus (AP) and juxtacanalicular connective tissue (JCT). (B) An image from a Y-27632-treated bovine eye, separation was found between the inner wall of the AP and JCT (double headed arrows). (C) Percent separation length (PSL) in bovine eyes was significantly increased in Y-27632- treated eyes compared to control eyes. (D) An image from a control monkey eye, the inner wall (IW) of Schlemm's canal (SC) appeared in contact with the underlying JCT matrix. (E) An image from a Y-27632-treated monkey eye, separation was found between the inner wall of SC and JCT (double headed arrows). (F) PSL in the JCT region was significantly increased in Y-27632-treated eyes compared to control eyes. TM, trabecular meshwork. (A–C) from Lu et al.²³; (D–F) from Lu et al.²⁴