Table 1.
Actinomycete strains active in one or more HTS programa
Active strains | Gram+b | Gram-c | FungiD |
---|---|---|---|
Total | 6211 | 3542 | 1362 |
Streptomyces | 2334 | 1553 | 627 |
Other classified | 2454 | 1152 | 357 |
Not classified | 1423 | 837 | 378 |
The table reports the number of strains that produced an extract possessing growth inhibitory activity against the indicated group of pathogens.
Activity against at least one of three S. aureus, two Enterococcus faecium or one Streptococcus pyogenes strains.
Activity against at least one of four E. coli, one Pseudomonas aeruginosa, one Acinetobacter baumannii or one Stenotrophomonas maltophilia strains.
Activity against at least one Candida albicans or one Aspergillus fumigatus strain; extracts likely to contain polyenes by a reversion assay have not been included.