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Growth and antibiotic production in Asparagine-starch medium. Strains used: S. clavuligerus ATCC 27064 (open symbols) and S. clavuligerus ΔccaR::tsr (closed symbols). A. Growth (circles) as measured by the DNA content. B. Cephamycin C (circles) or clavulanic acid (triangles) production. C. Holomycin production (squares).
