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Caspase recruitment domain-containing protein 11 (CARD11) silencing suppressed joint destruction in collagen-induced arthritis (CIA). (a) Representative haematoxylin and eosin (H&E) staining images (×10). (b) Representative Safranin-O staining images (×10). (c) Semi-quanitative score. Data are mean ± standard deviation (s.d.). *P < 0·05 versus control siRNA-treated group; n = eight mice per group.
