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. 2014 Apr 9;176(2):266–274. doi: 10.1111/cei.12277

Figure 2.

Figure 2

CD8+ mucosal-associated invariant T (MAIT) cells are specifically decreased in blood of inflammatory bowel diseases (IBD) patients. The proportion of CD8+, CD4+ and CD4–CD8– [double-negative (DN)] blood MAIT cells were analysed in IBD versus healthy donors. (a) One representative example per group of the proportion of CD8+, CD4+ and DN cells among CD3+Vα7.2+CD161hi MAIT cells. (b) Percentage of CD8+ (left), CD4+ (middle) and DN (right) MAIT cells among CD3+ T cells in the blood of healthy, Crohn's disease (CD) and ulcerative colitis (UC) patients. Data are analysed from the same set of patients as in Fig. 1. Statistical analysis of mean ± standard error of the mean (s.e.m.). **P < 0·05; *** P < 0·005.