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Effects of AT13387 and imatinib on KIT signaling in imatinib-sensitive and -resistant GIST cell lines. GIST882 (A), GIST430 (B), and GIST48 (C) cells were incubated with the indicated concentrations of AT13387 or imatinib (IM) for 24 hours. Samples were run by SDS-PAGE and immunoblotted with the indicated antibodies. This study was typical of at least 3 experiments.
