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Microbial synthesis of secondary bile acids from primary bile acids in the human distal gut. The oxidative and reductive arms of the pathway are enclosed within solid and dashed lines boxes, respectively. BaiB – bile acid CoA ligase; BaiA1/A2 - 3α-Hydroxysteroid Dehydrogenase; BaiCD - 3-oxo-Δ4-cholenoic acid oxidoreductase; BaiE - bile acid 7α dehydratase. Unidentified enzymes participating in the reductive arm are denoted by question mark.
