Table 2.
Cox proportional hazard regression model analysis for survival days and circadian clock gene expression in the 29 gastric cancer patients
| Relative expression of circadian clock gene | Hazard ratio | 95% CI | p value |
|---|---|---|---|
|
PER1 |
1.183 |
0.971-1.441 |
0.096 |
|
PER2 |
0.945 |
0.798-1.120 |
0.516 |
|
PER3 |
0.901 |
0.815-0.997 |
0.044 |
|
CRY1 |
0.879 |
0.761-1.015 |
0.079 |
|
CRY2 |
0.926 |
0.809-1.061 |
0.268 |
|
CKIϵ |
1.024 |
0.873-1.252 |
0.819 |
|
CLOCK |
0.891 |
0.706-1.124 |
0.328 |
| BMAL1 | 0.917 | 0.802-1.049 | 0.206 |
The relative expression of circadian clock genes in cancerous tissue/noncancerous tissues was calculated by 2-ΔΔC T. CI: confidence interval.