Table 1.
Baseline Characteristics
| Cell recipients Mean (range) or N (%) N = 23 |
Concurrent cooled Mean (range) or N (%) N = 82 |
P | |
|---|---|---|---|
| Gestational Age, wks | 38 (34, 40) | 39 (34, 41) | 0.10 |
| Birthweight, kg | 3130 (2120, 4660) | 3310 (1850, 4840) | 0.67 |
| Abruption | 1 (5) | 9 (12) | 0.44 |
| Cord prolapse | 3 (14) | 2 (3) | 0.08 |
| Non-reassuring fetal status | 9 (41) | 23 (32) | 0.45 |
| Cesarean delivery | 16 (70) | 48 (59) | 0.47 |
| Outborn | 6 (26) | 73 (88) | < 0.001 |
| SGAa | 1 (5) | 7 (8) | 0.45 |
| LGA | 2 (9) | 6 (7) | 0.99 |
| Males | 10 (44) | 56 (68) | 0.05 |
| African Americanb | 10 (50) | 32(40) | 0.52 |
| 5 minute Apgar ≤ 5 | 19 (83) | 61 (75%) | 0.58 |
| 10 minute Apgar ≤ 5 | 14 (61) | 42 (57%) | 0.81 |
| Cord pH | 6.99 (6.72, 7.26) | 6.96 (6.48, 7.44) | 0.82 |
| Base Deficit | 17 (8, 32) | 18 (3, 36) | 0.70 |
| Cord pH < 7 | 13 (57) | 47 (61) | 0.44 |
| Base deficit > 16 | 18 (78) | 65 (78) | 0.99 |
| NICHD scorec | 23 (15, 39) | 20 (8, 59) | 0.64 |
| NICHD score ≥ 30 | 5 (22) | 23 (27) | 0.79 |
| Seizures | 5 (22) | 29 (35) | 0.17 |
a
Small and large for gestational age measurements were defined using growth charts from U.S. births.24
b
20 cell recipients and 80 concurrently cooled with race reported.
c
NICHD score is an estimate of likelihood of positive outcome with cooling