Table 6.
Competing Risk Model Evaluating Risk of Pre-transplantation Death on the Waitlist or Within 90 Days of De-Listing of HPS vs Non-HPS Waitlist Candidatesa
| Variable | Multivariable SHR (95% CI) | P valueb |
|---|---|---|
| HPS | 0.41 (0.31–0.55) | <.001 |
| Age at listingc | 1.27 (1.23–1.31) | <.001 |
| Male sex | 0.85 (0.79–0.92) | <.001 |
| Race/ethnicity | <.001 | |
| White | 1 | |
| Black | 0.86 (0.78–0.95) | |
| Hispanic | 1.10 (0.98–1.25) | |
| Asian | 1.05 (0.97–1.12) | |
| Other | 1.12 (0.92–1.35) | |
| Initial laboratory MELD scored | 1.03 (1.02–1.03) | <.001 |
| Primary diagnosis | <.001 | |
| Hepatitis C | 1 | |
| Alcohol | 0.80 (0.77–0.83) | |
| Hepatitis B | 0.82 (0.74–0.91) | |
| NASH/cryptogenic | 0.80 (0.74–0.87) | |
| Cholestatic | 0.74 (0.67–0.82) | |
| Autoimmune | 0.81 (0.75–0.87) | |
| Other | 1.00 (0.89–1.12) | |
| Ascites before listing | 1.23 (1.12–1.34) | <.001 |
| Blood type | ||
| O | 1 | <.001 |
| A | 0.97 (0.92–1.02) | |
| B | 0.79 (0.73–0.86) | |
| AB | 0.49 (0.44–0.55) | |
| Initial serum albumin | 0.74 (0.69–0.79) | <.001 |
NASH, nonalcoholic steatohepatitis.
a
Competing risk Cox regression model, treating transplantation as a competing risk. Results reported as sub-hazard ratios (SHRs) instead of hazard ratios.
b
P value for multivariable hazard ratio.
c
Hazard for every increase in 10 years at listing.
d
SHR represents increased risk for every 1 MELD point.