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. Author manuscript; available in PMC: 2015 Apr 22.
Published in final edited form as: J Am Coll Cardiol. 2014 Feb 5;63(15):1542–1555. doi: 10.1016/j.jacc.2014.01.007

Figure 4. SLC35F3 and hypertension: Effects on early pathogenic (or “intermediate”) traits in twins and siblings.

Figure 4

Figure 4

Figure 4

Twin and sibling analyses were adjusted for sex and age.

A: SLC35F3 variant rs17514104 effects on systemic vascular resistance and stroke volume in twins and sibling pairs.

B: SLC35F3 variant rs17514104 effects on change in DBP and final DBP during cold stress.

C: SLC35F3 variant rs17514104 effects on sympathochromaffin exocytosis (secretion of SCG2 fragment secretoneurin) and systemic vascular resistance.