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Study design for digital autoradiography studies 1 and 2
| Amount of mAb per injection | Injected activity of each tracer per animal | |||||||
|---|---|---|---|---|---|---|---|---|
|
|
||||||||
| Study | Animals (n) | 2D03 (μg) | Control mAb (μg) | 131I-2D03 (MBq) | 125I-control mAb (MBq) | 125I-2D03 (MBq) | 131I-control mAb (MBq) | 18F-FDG (MBq) |
| 1 | 8 | 6.0 | 6.7 | 1.5 | 0.5 | - | - | 15 |
| 2 | 4 | 14.1 | 6.0 | - | - | 0.7 | 1.8 | 45 |
