Table 2.
Crude odds ratios and 95% confidence intervals for interest in predictive SNP testing for colorectal cancer risk for the overall study population and by intervention subgroup
| TeleCARE (n=121) | Control (n=151) | Overall (n=272) | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| N (%)* | OR (95% CI) | P | N (%)* | OR (95% CI) | P | N (%)* | OR (95% CI) | P | |
| Gender | 0.395 | 0.011 | 0.307 | ||||||
| Male | 34 (28.1) | 1.48 (0.58,3.80) | 63 (41.7) | 0.32 (0.13, 0.76) | 97 (35.7) | 0.74 (0.418, 1.32) | |||
| Female | 87 (71.9) | 1.00 (Reference) | 88 (58.3) | 1.00 (Reference) | 175 (64.3) | 1.00 (Reference) | |||
| Age | 0.051 | 0.049 | 0.003 | ||||||
| <45 | 37 (30.6) | 3.54 (1.10, 11.37) | 47 (31.1) | 4.66 (1.35, 16.06) | 84 (30.9) | 3.86 (1.74, 8.56) | |||
| 45–<60 | 59 (48.8) | 3.34 (1.18, 9.45) | 72 (47.7) | 2.19 (0.82, 5.87) | 131 (48.2) | 2.63 (1.33, 5.21) | |||
| ≥60 | 25 (20.7) | 1.00 (Reference) | 32 (21.2) | 1.00 (Reference) | 57 (21.0) | 1.00 (Reference) | |||
| Married | 0.647 | 0.104 | 0.151 | ||||||
| Yes | 94 (77.7) | 1.00 (Reference) | 119 (78.8) | 1.00 (Reference) | 213 (78.3) | 1.00 (Reference) | |||
| No | 27 (22.3) | 1.25 (0.46, 3.36) | 32 (21.2) | 2.93 (0.80, 10.82) | 59 (21.7) | 1.71 (0.82, 3.57) | |||
| Education | 0.856 | 0.742 | 0.905 | ||||||
| High school or less | 21 (17.4) | 1.38 (0.42, 4.57) | 23 (15.2) | 0.76 (0.22, 2.65) | 44 (16.2) | 1.00 (0.44, 2.29) | |||
| Some college | 53 (43.8) | 1.10 (0.45, 2.71) | 63 (41.7) | 0.71 (0.28, 1.78) | 116 (42.7) | 0.88 (0.48, 1.63) | |||
| College graduate | 47 (38.8) | 1.00 (Reference) | 65 (43.1) | 1.00 (Reference) | 112 (41.2) | 1.00 (Reference) | |||
| Income | 0.673 | 0.938 | 0.901 | ||||||
| <$30,000 | 21 (17.4) | 0.47 (0.15, 1.52) | 25 (16.6) | 1.37 (0.37, 5.11) | 46 (16.9) | 0.75 (0.34, 1.68) | |||
| $30,000–$49,999 | 21 (17.4) | 1.07 (0.31, 3,73) | 29 (19.2) | 1.22 (0.36, 4.16) | 50 (18.4) | 1.14 (0.49, 2.62) | |||
| $50,000–$69,999 | 23 (19.0) | 0.98 (0.30, 3.24) | 27 (17.9) | 0.91 (0.28, 2.96) | 50 (18.4) | 0.94 (0.42, 2.09) | |||
| ≥$70,000 | 42 (34.7) | 1.00 (Reference) | 55 (36.4) | 1.00 (Reference) | 97 (35.7) | 1.00 (Reference) | |||
| Refused | 14 (11.6) | 0.86 (0.20, 3.75) | 15 (9.9) | 0.73 (0.18, 2.93) | 29 (10.7) | 0.78 (0.30, 2.06) | |||
| Health insurance | 0.356 | 0.659 | 0.916 | ||||||
| Yes | 105 (86.8) | 1.00 (Reference) | 122 (80.8) | 1.00 (Reference) | 227 (83.5) | 1.00 (Reference) | |||
| No | 16 (13.2) | 0.60 (0.19, 1.86) | 29 (19.2) | 1.27 (0.43, 3.81) | 45 (16.5) | 0.96 (0.46, 2.02) | |||
| Personal healthcare provider | 0.888 | 0.662 | 0.807 | ||||||
| Yes | 84 (69.4) | 1.00 (Reference) | 96 (63.6) | 1.00 (Reference) | 180 (66.2) | 1.00 (Reference) | |||
| No | 37 (30.6) | 0.94 (0.39, 2.29) | 55 (36.4) | 0.83 (0.35, 1.95) | 92 (33.8) | 0.93 (0.52, 1.68) | |||
| Relatives with colorectal cancer diagnosis | 0.668 | 0.488 | 0.822 | ||||||
| 1 | 88 (72.7) | 1.00 (Reference) | 112 (74.7) | 1.00 (Reference) | 200 (73.8) | 1.00 (Reference) | |||
| ≥1 | 33 (27.3) | 1.21 (0.48, 3.05) | 38 (25.3) | 0.73 (0.29, 1.83) | 71 (26.2) | 0.93 (0.50, 1.75) | |||
| Rural/urban status | 0.881 | 0.797 | 0.969 | ||||||
| Urban | 92 (76.0) | 1.00 (Reference) | 119 (78.8) | 1.00 (Reference) | 211 (77.6) | 1.00 (Reference) | |||
| Rural | 29 (24.0) | 0.93 (0.37, 2.39) | 32 (21.2) | 1.14 (0.41, 3.21) | 61 (22.4) | 0.99 (0.51, 1.92) | |||
| Cancer worry score | 0.093 | 0.224 | 0.018 | ||||||
| Low | 43 (35.5) | 1.00 (Reference) | 50 (33.3) | 1.00 (Reference) | 93 (34.3) | 1.00 (Reference) | |||
| Moderate | 40 (33.1) | 0.96 (0.37, 2.49) | 44 (29.3) | 1.17 (0.43, 3.17) | 84 (31.0) | 1.02 (0.53, 1.97) | |||
| High | 38 (31.4) | 2.95 (0.98, 8.89) | 56 (37.3) | 2.45 (0.85, 7.10) | 94 (34.7) | 2.68 (1.29, 5.60) | |||
| Perceived severity | 0.026 | 0.914 | 0.153 | ||||||
| High | 76 (63.3) | 1.00 (Reference) | 84 (56.0) | 1.00 (Reference) | 160 (59.3) | 1.00 (Reference) | |||
| Low | 44 (36.7) | 0.38 (0.16, 0.88) | 66 (44.0) | 1.04 (0.45, 2.42) | 110 (40.7) | 0.66 (0.38, 1.17) | |||
| Perceived control | 0.231 | 0.751 | 0.745 | ||||||
| No control | 5 (4.1) | 0.32 (0.05, 2.21) | 12 (8.1) | 1.29 (0.25, 6.61) | 17 (6.3) | 0.84 (0.28, 2.52) | |||
| Some/complete control | 116 (95.9) | 1.00 (Reference) | 137 (92.0) | 1.00 (Reference) | 253 (93.7) | 1.00 (Reference) | |||
| Risk behavior score | 0.761 | 0.289 | 0.822 | ||||||
| 1 | 29 (25.4) | 0.77 (0.23, 2.57) | 40 (28.0) | 1.84 (0.58, 5.81) | 69 (26.9) | 1.22 (0.55, 2.71) | |||
| 2 | 53 (46.5) | 0.69 (0.24, 1.98) | 67 (46.9) | 2.24 (0.79, 6.34) | 120 (46.7) | 1.23 (0.61, 2.49) | |||
| 3 | 32 (28.1) | 1.00 (Reference) | 36 (25.2) | 1.00 (Reference) | 68 (26.5) | 1.00 (Reference) | |||
| Intervention group | 0.020 | ||||||||
| Control | 151 (55.5) | 1.97 (1.12, 3.47) | |||||||
| Intervention | 121 (44.5) | 1.00 (Reference) | |||||||
|
| |||||||||
| Continuous variables | Mean (SD) | ||||||||
|
| |||||||||
| Optimism | 15.9 (3.9) | 0.95 (0.85, 1.06) | 0.342 | 16.3 (3.8) | 1.06 (0.95, 1.18) | 0.265 | 16.1 (3.9) | 1.01 (0.94, 1.08) | 0.850 |
| Cancer fear | 2.2 (0.8) | 2.08 (1.16, 3.73) | 0.017 | 2.3 (0.8) | 1.38 (0.79, 2.39) | 0.250 | 2.3 (0.8) | 1.69 (1.15, 2.48) | 0.008 |
| Anxiety | 16.9 (5.2) | 1.03 (0.95, 1.11) | 0.461 | 16.9 (5.0) | 0.98 (0.91, 1.07) | 0.694 | 16.9 (5.1) | 1.01 (0.95, 1.07) | 0.765 |
| Perceived Susceptibility | 14.7 (2.3) | 1.11 (0.92, 1.33) | 0.261 | 14.5 (2.7) | 1.07 (0.91, 1.25) | 0.398 | 14.6 (2.5) | 1.07 (0.96, 1.20) | 0.214 |
*
Percentages do not total 100% due to rounding