Table 1. Patient and Disease Characteristics.
| Variable | Number (%) | |
|---|---|---|
| Mean age at diagnosis (range) | 59.4 years (38-82 years) | |
| Race | White | 35 (81.4%) |
| Black | 8 (18.6%) | |
| BMI | <30 | 32 (74.4%) |
| ≥30 | 11 (25.6%) | |
| Charlson co-morbidity index | 0 | 27 (62.8%) |
| ≥1 | 16 (37.2%) | |
| Year of diagnosis | 1995-2000 | 11 (25.6%) |
| 2001-2006 | 17 (39.5%) | |
| 2007-2011 | 15 (34.9%) | |
| Cancer type | Uterine | 13 (30.2%) |
| Cervix | 11 (25.6%) | |
| Ovarian/Fallopian tube/Primary peritoneal | 17 (39.5%) | |
| Vulva/Vagina | 2 (4.7%) | |
| Stage | I/II | 16 (37.2%) |
| III/IV | 21 (48.8%) | |
| Unknown | 6 (14.0%) | |
| Cancer-directed surgery | Yes | 31 (72.1%) |
| No | 11 (25.6%) | |
| Unknown | 1 (2.3%) | |
| Radiation | Yes | 21 (48.8%) |
| No | 20 (46.5%) | |
| Unknown | 2 (4.7%) | |
| Chemotherapy | Yes | 34 (79.1%) |
| No | 6 (14.0%) | |
| Unknown | 3 (6.9%) | |
| Chemotherapy Regimen | <2 | 17 (50.0%) |
| ≥2 | 14 (41.2%) | |
| Unknown | 3 (8.8%) | |
| Site of perforation | Small bowel | *21 (48.8%) |
| large bowel | *10 (23.3%) | |
| Sigmoid colon | 9 (20.9%) | |
| Stomach | 1 (2.3%) | |
| Unknown | 4 (9.3%) | |
| Extent of cancer present at the time of perforation | No evidence of disease | 8 (18.6%) |
| Microscopic disease/Localized disease | 10 (23.3%) | |
| Peritoneal carcinomatosis/Distant metastasis | 22 (51.1%) | |
| Unknown | 3 (7.0%) | |
| Ca-125 | <100 | 10 (23.3%) |
| ≥100 | 16 (37.2%) | |
| Unknown | 17 (39.5%) | |
| Prior or concurrent bowel obstruction | Yes | 24 (55.8%) |
| No | 17 (39.5%) | |
| Unknown | 2 (4.7%) | |
| Management of perforation | Conservative | 15 (34.9%) |
| Surgical | 28 (65.1%) | |
*
Perforation was present in small- and large bowel in 2 patients.